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  • 51 Why has there been so little progress on Alzheimer's disease? (freakonomics.com)
    by chiefalchemist an hour ago | 17 comments
  • 154 USB Cheat Sheet (2022) (fabiensanglard.net)
    by gwerbret 4 hours ago | 46 comments
  • 271 The Free Universal Construction Kit (fffff.at)
    by robinhouston 4 days ago | 51 comments
  • 79 OpenAI Privacy Filter (openai.com)
    by tanelpoder 3 days ago | 14 comments
  • 522 1-Bit Hokusai's "The Great Wave" (2023) (hypertalking.com)
    by stephen-hill 3 days ago | 87 comments
  • 27 Agents Aren't Coworkers, Embed Them in Your Software (feldera.com)
    by gz09 2 hours ago | 8 comments
  • 176 Using coding assistance tools to revive projects you never were going to finish (blog.matthewbrunelle.com)
    by speckx 9 hours ago | 106 comments
  • 15 Optimizing Datalog for the GPU (dl.acm.org)
    by tosh 3 days ago | discuss
  • 64 America's Geothermal Breakthrough (oilprice.com)
    by sleepyguy 6 hours ago | 73 comments
  • 78 The Joy of Folding Bikes (blog.korny.info)
    by pavel_lishin 3 days ago | 47 comments
  • 28 Flickr: The first and last great photo platform (petapixel.com)
    by Nrbelex 3 days ago | 6 comments
  • 30 Math Is Hard – OpenBSD Stories (miod.online.fr)
    by signa11 2 days ago | discuss
  • 23 Her Life Savings Mysteriously Disappeared After a Systems Glitch (nytimes.com)
    by danso 2 hours ago | 13 comments
  • 544 New 10 GbE USB adapters are cooler, smaller, cheaper (jeffgeerling.com)
    by calcifer 20 hours ago | 318 comments
  • 92 Simulacrum of Knowledge Work (blog.happyfellow.dev)
    by thehappyfellow 8 hours ago | 33 comments
  • 59 How Hard Is It to Open a File? (blog.sebastianwick.net)
    by ffin 2 days ago | 8 comments
  • 69 Mine, an IDE for Coalton and Common Lisp (coalton-lang.github.io)
    by varjag 8 hours ago | 20 comments
  • 104 Desmond Morris has died (bbc.com)
    by martey 5 days ago | 17 comments
  • 156 What async promised and what it delivered (causality.blog)
    by zdw 4 days ago | 175 comments
  • 159 Martin Galway's music source files from 1980's Commodore 64 games (github.com)
    by ingve 15 hours ago | 21 comments
  • 41 Show HN: Kloak, A secret manager that keeps K8s workload away from secrets (getkloak.io)
    by neo2006 7 hours ago | 35 comments
  • 126 GPT‑5.5 Bio Bug Bounty (openai.com)
    by Murfalo 11 hours ago | 97 comments
  • 147 Discret 11, the French TV encryption of the 80s (fabiensanglard.net)
    by adunk 14 hours ago | 26 comments
  • 60 Lute: A Standalone Runtime for Luau (lute.luau.org)
    by vrn-sn 3 days ago | 11 comments
  • 37 Colorado Adds Open-Source Exemption to Age-Verification Bill (fosstodon.org)
    by terminalbraid 3 hours ago | 2 comments
  • 99 Can you stop beans from making you gassy? (seriouseats.com)
    by jstrieb 5 hours ago | 78 comments
  • 50 Which one is more important: more parameters or more computation? (2021) (parl.ai)
    by jxmorris12 a day ago | 9 comments
  • 50 Insights into firewood use by early Middle Pleistocene hominins (sciencedirect.com)
    by wslh 3 days ago | 20 comments
  • 110 A web-based RDP client built with Go WebAssembly and grdp (github.com)
    by mariuz 15 hours ago | 43 comments
  • 277 Plain text has been around for decades and it’s here to stay (unsung.aresluna.org)
    by rbanffy a day ago | 137 comments