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  • 417 CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
    by gmays 5 hours ago | 109 comments
  • 121 I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
    by ibobev 2 hours ago | 78 comments
  • 89 How to setup a local coding agent on macOS (ikyle.me)
    by kkm 2 hours ago | 27 comments
  • 144 Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
    by marc__1 a day ago | 89 comments
  • 74 Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
    by iweczek 3 hours ago | 30 comments
  • 75 A PDF that changes based on how its read (sgaud.com)
    by SarthakGaud 3 hours ago | 38 comments
  • 126 Slightly reducing the sloppiness of AI generated front end (envs.net)
    by FergusArgyll 5 hours ago | 81 comments
  • 76 Looking Forward to Postgres 19: It's About Time (pgedge.com)
    by xngbuilds 3 hours ago | 20 comments
  • 18 Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
    by arcb 3 hours ago | 8 comments
  • 38 Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
    by bookofjoe 3 hours ago | 35 comments
  • 127 A dumpster arrived behind my university's library (yalereview.org)
    by mooreds 5 hours ago | 104 comments
  • 72 Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
    by ibobev 4 hours ago | 43 comments
  • 39 There Is Life Before Main in Rust (grack.com)
    by mmastrac a day ago | 12 comments
  • 1329 AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
    by xiaoyu2006 15 hours ago | 478 comments
  • 41 Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
    by jtlebigot 5 hours ago | 11 comments
  • 13 Cosmodial Sky Atlas (killedbyapixel.github.io)
    by memalign 2 hours ago | 1 comments
  • 115 Maxproof (arxiv.org)
    by ilreb 8 hours ago | 9 comments
  • 102 "Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
    by speckx 2 hours ago | 98 comments
  • Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
    7 hours ago   job
  • 276 A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
    by FergusArgyll 5 hours ago | 178 comments
  • 29 Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
    by datafreak_ 4 hours ago | 8 comments
  • 200 WASI 0.3 (bytecodealliance.org)
    by mavdol04 6 hours ago | 81 comments
  • 1397 If you are asking for human attention, demonstrate human effort (tombedor.dev)
    by jjfoooo4 21 hours ago | 441 comments
  • 107 Keygen.music (keygen.music)
    by soupspaces 4 hours ago | 63 comments
  • 59 New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
    by 1vuio0pswjnm7 3 hours ago | 40 comments
  • 250 How we made hit video game Prince of Persia (theguardian.com)
    by msephton 3 days ago | 101 comments
  • 59 I Won't Buy You a Coffee (hakkerman.eu)
    by speckx an hour ago | 46 comments
  • 49 Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
    by _____k 7 hours ago | 5 comments
  • 350 Kimi K2.7-Code: open-source coding model with better token efficiency (huggingface.co)
    by nekofneko 9 hours ago | 192 comments
  • 43 Show HN: Script to bulk delete Claude chats from the web UI (github.com)
    by ML0037 5 hours ago | 16 comments