Hamilton's Pharmacopia covers this topic, including an interview with the supposed author, then later corrected, then the true author revealed. Definitely worth checking out.
Every time I find one of these in my backyard with my dog, I have to spray my dog’s mouth out with the hose for 5 minutes. Psychedelic, but also very toxic.
A couple groups are trying to commercialize it. There have been some trials, but they're all relatively limited by depression trial standards. Double-blind is impossible because the participants know 100% if they've received it or not. Someone volunteering to sign up for a depression study to receive psychedelic drugs is probably a believer that they work, so the placebo groups end up disappointed and the active groups are happy they got assigned the psychedelic they signed up.
They followed participants for 8 days, which is pretty disappointing. They really need to follow people for several months to see if anything holds or if it's a short-term placebo effect that wears off.
You don't need anything more than psilocybin and some weed from time to time.
Anything else is just unnecessary noise and introduces vulnerabilities to your Fortress of Mind.
Backdoor here, trapdoor here, tunnel there. Before you know it, your psyche collapses under all the brain neuroplasticity. Mind cannot form any shape at all.
Truly terrible thought so be careful my people. Don't malleableize yourself into a goo.
It is the bilion dollar industrial complex that sold you solution to the problem created by the very same system. Just take a pill.
It's ingenious really.
Create the problem, sell the solution.
I am rich generally speaking and I have privilege to see everything from my high vantage point.
From here I can easily see how life looks if you can afford to say: No thank you.
I don't even understand the very concept of suicide or depression. It seems fantastical. Because, I am outside the cruel system or rather I am at the steer in some capacity.
this post just demonstrates the lack of sympathy/empathy so many rich people seem to have for others. There is a huge difference between taking pills designed to eternally treat symptoms and never the root cause, vs a plant medicine that might actually address the root cause of a problem. Bufo unfortunately has the added problem of coming from an animal rather than a plant, I agree with another post that suggests using synthetic where possible, but one should also not give up the opportunity to do life-changing personal development...
This is an endangered species getting massively abused by the wellness "shaman" industry. It fucking sucks. Just use synthetic 5me0-dmt if you really must do a goofy vision quest larp.
Hamilton's Pharmacopia covers this topic, including an interview with the supposed author, then later corrected, then the true author revealed. Definitely worth checking out.
Every time I find one of these in my backyard with my dog, I have to spray my dog’s mouth out with the hose for 5 minutes. Psychedelic, but also very toxic.
Have any studies been done on this particular psychedelic? I'm curious.
A couple groups are trying to commercialize it. There have been some trials, but they're all relatively limited by depression trial standards. Double-blind is impossible because the participants know 100% if they've received it or not. Someone volunteering to sign up for a depression study to receive psychedelic drugs is probably a believer that they work, so the placebo groups end up disappointed and the active groups are happy they got assigned the psychedelic they signed up.
One of the latest studies: https://jamanetwork.com/journals/jamapsychiatry/fullarticle/...
They followed participants for 8 days, which is pretty disappointing. They really need to follow people for several months to see if anything holds or if it's a short-term placebo effect that wears off.
plenty of scientific and not-really-scientific links available at erowid for 5-meo-dmt
https://www.erowid.org/chemicals/5meo_dmt/5meo_dmt.shtml
scientific references specifically at https://www.erowid.org/references/refs.php?S=5meo_dmt
https://en.wikipedia.org/wiki/5-MeO-DMT has some references and the "further reading" links might have way more
Most recent I know of: https://www.psychiatrictimes.com/view/blp-003-for-treatment-...
Mebufotenin is 5-MeO-DMT
Completely fascinating video on this topic just recently:
https://www.wsj.com/video/the-race-to-commercialize-the-worl...
People really overthink drugs.
You don't need anything more than psilocybin and some weed from time to time.
Anything else is just unnecessary noise and introduces vulnerabilities to your Fortress of Mind.
Backdoor here, trapdoor here, tunnel there. Before you know it, your psyche collapses under all the brain neuroplasticity. Mind cannot form any shape at all.
Truly terrible thought so be careful my people. Don't malleableize yourself into a goo.
hmmm; I really don’t feel like I need weed or shrooms from time to time. I’m ok the way I am.
I’ve used both a lot.
It’s inaccurate to frame weed and psilo as “necessary”.
YMMV by person, their neurochemistry, and their living environment. I need a stimulant for my specific biology to adapt to modern expectations.
You don't need anything.
It is the bilion dollar industrial complex that sold you solution to the problem created by the very same system. Just take a pill.
It's ingenious really.
Create the problem, sell the solution.
I am rich generally speaking and I have privilege to see everything from my high vantage point. From here I can easily see how life looks if you can afford to say: No thank you.
I don't even understand the very concept of suicide or depression. It seems fantastical. Because, I am outside the cruel system or rather I am at the steer in some capacity.
this post just demonstrates the lack of sympathy/empathy so many rich people seem to have for others. There is a huge difference between taking pills designed to eternally treat symptoms and never the root cause, vs a plant medicine that might actually address the root cause of a problem. Bufo unfortunately has the added problem of coming from an animal rather than a plant, I agree with another post that suggests using synthetic where possible, but one should also not give up the opportunity to do life-changing personal development...
Your comment isn’t useful to anyone but you
you have no idea who the person you are responding to is or what their circumstances are
Recently published, curious if anyone has read it: https://www.penguinrandomhouse.com/books/735472/the-ego-trip...
He wrote a nice New Yorker article a few years ago:
https://www.newyorker.com/magazine/2022/03/28/the-pied-piper...
Find your soulmate, Homer!
Can we please leave the fucking toads alone?
This is an endangered species getting massively abused by the wellness "shaman" industry. It fucking sucks. Just use synthetic 5me0-dmt if you really must do a goofy vision quest larp.
Hmm. I am all for leaving animals alone, but their Wikipedia page says their status is “secure” and of “least concern”.
So yeah, let the frogs be, but I don’t think we should invent (hallucinate, in this case, perhaps?) reasons why…
HAMILTON,BUFOTENINE YOU NEED TO MAKE A VIDEO. xD
Anyone watch Hamiltons pharmacopeia
https://www.youtube.com/watch?v=vAg5kAcw-TA
I do.