This is great news! I think people forget how anti-skin cancer protocols even as simple as applying suntan lotion weren't as popular as recent as 50-60 years ago. Lots of "sun children" of the 50s and 60s are now feeling the repercussions of only applying baby oil and are getting hit with lots of melanoma.
+1. Also, just to call out, it doesn't need to be _warm_ for you to need sunblock. Even when it's cooler / cloudier out there you can still get skin damage. Look for UV rating rather than temperature. Conversely, it being hot doesn't imply high-UV either.
I didn't know about the UV index or what it meant until like three years ago. It blows my mind I went that long without understanding. It was actually wonderful to learn that I could just see if I needed sunblock based on a 0-10 scale.
We never wore sunscreen as kids because we didn't burn. I probably have had three sunburns in my life. Learned once I became an adult that that wasn't sound logic...
Huge, uplifting, news, hope the study will bear further fruit. Considering that 90% of all clinical trials fail, it's good to read about a truly promising one for once.
Ever since I first heard of them a decade ago, it seemed that mRNA therapeutic vaccines were going to be the next wave of massive improvements in care. It's taken a bit longer than I had expected, and it's not that mRNA is the only way to make these sorts of vaccines, it's just so much better than the alternatives.
Even if you were to optimally price in all available information you still have uncertainty of what will actually happen. i.e. A 1 dollar coin flip has an expected value of 50c before it’s thrown and it will collapse either to zero or to one after the uncertainty is resolved.
I have 1000 shares of mRNA woohoo! For all the hate I have for the COVID vaccine, I still believe in the underlying technology and I put my money where my mouth was and bought around $20. I think this is just the first of many cancer treatments mRNA will bring and I’m very excited for the future of the technology.
Can you clarify that? It saved 100K+ lives even by incredibly conservative estimates, and allowed life to returned to normal at least a year earlier than otherwise.
I can't speak for other people but I was upset to enter a medical era where bureaucrats were forcing medical decisions on me. I was forced to get it or lose my job despite 1) working remotely, 2) having already had Covid and 3) being healthy and not at risk of Covid death but being the largest risk for myocarditis.
I thankfully figured out my young children didn't need COVID vaccines. A little grumpy that the medical profession pushed them on children when they really did know that children weren't at risk nearly as much by then.
Sloppy thinking like this is how we get RFK, love him or loathe him.
I don't recall it being as polarizing outside of the US, where there was a larger group of anti-vaxxers to begin with. But that might be my "outside US" bubble.
There is a legitimate discussion of what can be mandated you do to your body.
However, that discussion was largely side-tracked by the massive amount of disinformation (eg, "Plandemic") that circulated online. There are people who to this day swear that COVID-19 was just like the flu and simultaneously claim that the vaccine spike proteins have killed around 20M people. Not just crackpots, but people with reach, like Brett Weinstein on Joe Rogan's podcast.
This is great news! I think people forget how anti-skin cancer protocols even as simple as applying suntan lotion weren't as popular as recent as 50-60 years ago. Lots of "sun children" of the 50s and 60s are now feeling the repercussions of only applying baby oil and are getting hit with lots of melanoma.
+1. Also, just to call out, it doesn't need to be _warm_ for you to need sunblock. Even when it's cooler / cloudier out there you can still get skin damage. Look for UV rating rather than temperature. Conversely, it being hot doesn't imply high-UV either.
I didn't know about the UV index or what it meant until like three years ago. It blows my mind I went that long without understanding. It was actually wonderful to learn that I could just see if I needed sunblock based on a 0-10 scale.
We never wore sunscreen as kids because we didn't burn. I probably have had three sunburns in my life. Learned once I became an adult that that wasn't sound logic...
Huge, uplifting, news, hope the study will bear further fruit. Considering that 90% of all clinical trials fail, it's good to read about a truly promising one for once.
This appears to be a potentially huge win for health. The market has Moderna up 153%, which is some sort of validation I suppose.
Related stories:
https://www.fiercebiotech.com/biotech/merck-and-modernas-per...
https://www.reuters.com/legal/litigation/merck-moderna-say-m...
https://www.wsj.com/health/pharma/moderna-merck-vaccine-succ...
oh nice. If it goes up another 100% I may not lose money on this stock anymore.
I mean, this appears to be validation of mRNA in general, right?
Saving a couple million people in the pandemic wasn’t validation enough?
100%, what I meant to say was that it proves that it wasn't somehow a one trick pony.
And if it doubles after that, I may even beat a passive S&P 500 investment.
Ever since I first heard of them a decade ago, it seemed that mRNA therapeutic vaccines were going to be the next wave of massive improvements in care. It's taken a bit longer than I had expected, and it's not that mRNA is the only way to make these sorts of vaccines, it's just so much better than the alternatives.
I'm very very excited to see what comes next.
I listened to a great podcast on this just a month ago - too bad that I thought all of this would obviously be priced in already… https://virological.podigee.io/51-21-cancer-vaccines-how-the...
Even if you were to optimally price in all available information you still have uncertainty of what will actually happen. i.e. A 1 dollar coin flip has an expected value of 50c before it’s thrown and it will collapse either to zero or to one after the uncertainty is resolved.
Hard to price in the political factors now involved in Moderna's success or lack of success.
I don't believe the efficient market hypothesis. However even if you do, new information has arrived and that will affect the price.
I have 1000 shares of mRNA woohoo! For all the hate I have for the COVID vaccine, I still believe in the underlying technology and I put my money where my mouth was and bought around $20. I think this is just the first of many cancer treatments mRNA will bring and I’m very excited for the future of the technology.
> For all the hate I have for the COVID vaccine
Can you clarify that? It saved 100K+ lives even by incredibly conservative estimates, and allowed life to returned to normal at least a year earlier than otherwise.
I can't speak for other people but I was upset to enter a medical era where bureaucrats were forcing medical decisions on me. I was forced to get it or lose my job despite 1) working remotely, 2) having already had Covid and 3) being healthy and not at risk of Covid death but being the largest risk for myocarditis.
Is that when you entered that era? Or did you enter it when you were a newborn in the hospital, or a kid entering school?
I thankfully figured out my young children didn't need COVID vaccines. A little grumpy that the medical profession pushed them on children when they really did know that children weren't at risk nearly as much by then.
Sloppy thinking like this is how we get RFK, love him or loathe him.
What are the reasons for the hate of the COVID vaccine?
Probably one of the most polarizing issues of the last 5 years.
I don't recall it being as polarizing outside of the US, where there was a larger group of anti-vaxxers to begin with. But that might be my "outside US" bubble.
And, critically, a malignant narcissist in the highest office.
There is a legitimate discussion of what can be mandated you do to your body.
However, that discussion was largely side-tracked by the massive amount of disinformation (eg, "Plandemic") that circulated online. There are people who to this day swear that COVID-19 was just like the flu and simultaneously claim that the vaccine spike proteins have killed around 20M people. Not just crackpots, but people with reach, like Brett Weinstein on Joe Rogan's podcast.
Probably disinformation.